Necrotising fasciitis in a patient receiving infliximab for rheumatoid arthritis.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 11796874.
- Also identified by PMC identifier 1742233.
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Abstract
A case of necrotising fasciitis in a patient receiving infliximab, an antitumour necrosis factor alpha (TNF-alpha) agent for rheumatoid arthritis, is presented. A widespread confluent, erythematous, pustular skin rash was the presenting sign. There was no fever throughout this admission. beta-Haemolytic group A streptococcus was isolated from blood cultures and skin swabs. The adductor muscles and fascia around the site of a previous hip arthroplasty were necrotic on exploration. The case highlights the risk of severe sepsis in patients on anti-TNF-alpha treatment.
Medical subject headings
- Antibodies, Monoclonal
- Antirheumatic Agents
- Arthritis, Rheumatoid
- Fasciitis, Necrotizing