Prenatal ultrasonographic diagnosis of nasal bone abnormalities in three fetuses with Down syndrome.

Sonek, Jiri D; Nicolaides, Kypros H · Am J Obstet Gynecol · 2002

case_report · Level V

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Abstract

Facial abnormalities are common in neonates with Down syndrome. This report describes nasal bone abnormalities in 3 unselected fetuses with Down syndrome detected prenatally by ultrasonography. Two of the fetuses had ultrasonographically undetectable nasal bones and 1 had a nasal bone measurement that was below the 2.5th percentile of the normal distribution for that gestational age.

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