Necrotic seminoma of the testis: establishing the diagnosis with Masson trichrome stain and immunostains.

Florentine, Barbara D; Roscher, Arno A; Garrett, Jerry; Warner, Nancy E · Arch Pathol Lab Med · 2002

case_report · Level V

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Abstract

We describe an infarcted mass in the testis containing "ghost" cells suspicious for neoplasm. The entire lesion was necrotic. A Masson trichrome stain greatly improved nuclear and cytologic detail, confirming the suspicion of neoplasm. Placental alkaline phosphatase revealed specific membrane staining of the neoplastic cells and established a diagnosis of seminoma. Masson trichrome plus selected immunostains offer a promising approach to the diagnosis of certain necrotic neoplasms.

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