Multiple sclerosis-associated retrovirus (MSRV) in Sardinian MS patients.
cross_sectional · Level IV
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Abstract
Blood and CSF of Sardinian patients with MS and neurologic control subjects were tested for MS-associated retrovirus (MSRV). CSF detection in MS was 50% at clinical onset, increasing with temporal disease progression, and 40% in control subjects. In blood, MSRV was detected in all MS patients, in most patients with inflammatory neurologic diseases, and rarely in healthy blood donors. MSRV may represent a marker of neurologic diseases of inflammatory origin.
Medical subject headings
- Multiple Sclerosis
- Retroviridae
- Retroviridae Infections