Gene therapy and solid-organ transplantation.
review · Level V
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- Record sourced from PubMed, PMID 11841614.
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Abstract
Recent developments in transplantation medicine improved the short- and long-term survival of solid-organ transplantation. However, chronic allograft rejection, the side effects of the long-term immunosuppressive treatment, and organ shortage are still the major obstacles to achieving long-term survival. Gene therapy has the potential to meet these challenges and has unique advantages in transplantation. In this review we summarize the studies using gene therapy in solid-organ transplantation.
Medical subject headings
- Genetic Therapy
- Graft Rejection