Generating samples under a Wright-Fisher neutral model of genetic variation.
basic_science · Level V
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Abstract
A Monte Carlo computer program is available to generate samples drawn from a population evolving according to a Wright-Fisher neutral model. The program assumes an infinite-sites model of mutation, and allows recombination, gene conversion, symmetric migration among subpopulations, and a variety of demographic histories. The samples produced can be used to investigate the sampling properties of any sample statistic under these neutral models.
Medical subject headings
- Genetic Variation
- Models, Genetic
- Software