Lepirudin anticoagulation for heparin-induced thrombocytopenia.
case_report · Level V
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Abstract
Lepirudin is indicated for anticoagulation in patients with heparin-induced thrombocytopenia (HIT). We describe 2 cases of HIT and thrombosis in children with heart disease, including one that required extracorporeal membrane oxygenation. Lepirudin, dosed in the recommended adult weight--based fashion, was an effective antithrombotic agent in pediatric patients with HIT.
Medical subject headings
- Anticoagulants
- Hirudin Therapy
- Hirudins
- Recombinant Proteins
- Thrombocytopenia