A rendezvous before rejection: where do T cells meet transplant antigens?
editorial · Level V
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- Record sourced from PubMed, PMID 11875489.
- Also identified by PMC identifier 4471866.
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Abstract
Interactions between recipient T cells and donor endothelial graft cells may be an important mechanism for both acute and chronic rejection of vascularized allografts. This finding provides a starting point for investigations to develop novel ways of inducing long-lasting immunologic tolerance to donor antigens.
Medical subject headings
- Endothelium, Vascular
- Graft Rejection
- Histocompatibility Antigens
- T-Lymphocytes