Cooperation between complexes that regulate chromatin structure and transcription.

Narlikar, Geeta J; Fan, Hua-Ying; Kingston, Robert E · Cell · 2002

review · Level V

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Abstract

Chromatin structure creates barriers for each step in eukaryotic transcription. Here we discuss how the activities of two major classes of chromatin-modifying complexes, ATP-dependent remodeling complexes and HAT or HDAC complexes, might be coordinated to create a DNA template that is accessible to the general transcription apparatus.

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