Protein folding and unfolding at atomic resolution.

Fersht, Alan R; Daggett, Valerie · Cell · 2002

basic_science · Level V

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Abstract

Experiment and simulation are now conspiring to give atomic-level descriptions of protein folding relevant to folding, misfolding, trafficking, and degradation in the cell. We are on the threshold of predicting those protein folding events using simulation that has been carefully benchmarked by experiment.

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