fMRI/EEG in paroxysmal activity elicited by elimination of central vision and fixation.

Iannetti, G D; Di Bonaventura, C; Pantano, P; Giallonardo, A T; Romanelli, P L; Bozzao, L; Manfredi, M; Ricci, G B · Neurology · 2002

case_series · Level IV

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Abstract

Using functional MRI (fMRI) with concurrent EEG monitoring the authors studied cortical activation associated with epileptiform discharges in three patients with fixation-off sensitivity. The EEG paroxysmal activity elicited by eliminating central vision correlated significantly with an increased blood oxygen level-dependent signal in the extrastriate cortex (Brodmann areas 19 and 37). fMRI provides a unique opportunity for localizing precisely the cortical areas generating paroxysmal activity in patients with fixation-off sensitivity.

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