CASA: a server for the critical assessment of protein sequence alignment accuracy.

Kahsay, Robel Y; Wang, Guoli; Dongre, Nataraj; Gao, Guang; Dunbrack, Roland L · Bioinformatics · 2002

other · Level V

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Abstract

A public server for evaluating the accuracy of protein sequence alignment methods is presented. CASA is an implementation of the alignment accuracy benchmark presented by Sauder et al. (Proteins, 40, 6-22, 2000). The benchmark currently contains 39321 pairwise protein structure alignments produced with the CE program from SCOP domain definitions. The server produces graphical and tabular comparisons of the accuracy of a user's input sequence alignments with other commonly used programs, such as BLAST, PSI-BLAST, Clustal W, and SAM-T99. The server is located at http://capb.dbi.udel.edu/casa.

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