The genetic jigsaw of inflammatory bowel disease.
review · Level V
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- Record sourced from PubMed, PMID 11953330.
- Also identified by PMC identifier 1867682.
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Abstract
Following a prolonged period of relative inertia, real progress has been made in the past few years in understanding the pathogenesis of the chronic inflammatory bowel diseases, Crohn's disease and ulcerative colitis. Clinical experience, epidemiological studies, and molecular genetics have provided strong evidence that both genetic and environmental factors are important in disease pathogenesis, and gene-environmental interaction determines disease susceptibility and behaviour.
Medical subject headings
- Inflammatory Bowel Diseases