Antigenic variation and allelic exclusion.

Borst, Piet · Cell · 2002

review · Level V

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Abstract

Cells often express only one gene from a set of two or more. African trypanosomes appear to accomplish this monoallelic expression by segregating the selected gene into a specific nuclear body. The possibility that such a structure might explain monoallelic expression in other multigene systems is discussed here.

Medical subject headings