Immunoadsorption inferior to plasma exchange in a patient with chronic inflammatory demyelinating polyradiculoneuropathy.
case_report · Level V
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- Record sourced from PubMed, PMID 11971054.
- Also identified by PMC identifier 1737854.
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Abstract
Staphylococcal protein A immunoadsorption and plasma exchange were compared for treating chronic inflammatory demyelinating polyradiculoneuropathy. In a single patient, plasma exchange had a more beneficial effect than immunoadsorption on clinical outcome measures. Serum IgM antibody activity to peripheral nerve fell significantly following plasma exchange. Serum IgM and IgA fell more and IgG less after plasma exchange than after immunoadsorption. The superior efficacy of plasma exchange to immunoadsorption in this case may have been the result of removal of an IgM antibody.
Medical subject headings
- Plasma Exchange
- Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
- Staphylococcal Protein A