Exercise-induced muscle "burning," fatigue, and hyper-CKemia: mtDNA T10010C mutation in tRNA(Gly).
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 11971101.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A 42-year-old woman presented with myopathy and without a family history of neuromuscular disorder. Muscle biopsy showed ragged red fibers and reduced activities of mitochondrial respiratory chain enzyme complexes I, III, and IV. Analysis of mitochondrial DNA revealed a heteroplasmic T10010C mutation in the transfer RNA glycine gene.
Medical subject headings
- Creatine Kinase
- DNA, Mitochondrial
- Exercise
- Mitochondrial Myopathies
- Muscle Fatigue
- Mutation
- RNA, Transfer, Gly