The influences of maternal albumin concentrations on the placental transfer of propofol in human dually perfused cotyledon in vitro.
basic_science · Level V
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Abstract
These results indicate that fetal exposure to propofol can vary considerably depending on maternal plasma albumin concentration. A fractional change in the maternal protein binding of propofol can result in a relatively large difference in fetal exposure.
Medical subject headings
- Anesthetics, Intravenous
- Maternal-Fetal Exchange
- Placenta
- Propofol
- Serum Albumin