An invitation to T and more: notch signaling in lymphopoiesis.

Allman, David; Punt, Jennifer A; Izon, David J; Aster, Jon C; Pear, Warren S · Cell · 2002

review · Level V

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Abstract

Cell fate decisions in metazoans are regulated by Notch signals. During lymphoid development, Notch influences a series of cell fate decisions involving multipotent progenitors. This review focuses on current views and lingering uncertainties about Notch function in lymphoid cells.

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