Transcription: tantalizing times for T cells.
review · Level V
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- Record sourced from PubMed, PMID 11983157.
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Abstract
The T helper lymphocyte is responsible for orchestrating an appropriate immune response to pathogens. To do so, it has evolved into two specialized subsets that direct type 1 and type 2 immunity. Here, we discuss the genetic programs that control lineage commitment of progenitor T helper cells along each of these pathways.
Medical subject headings
- Cell Differentiation
- Cell Lineage
- Gene Expression Regulation
- Nuclear Proteins
- T-Lymphocytes