Cytokine signaling in 2002: new surprises in the Jak/Stat pathway.
review · Level V
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Abstract
The importance of Jak-Stat pathway signaling in regulating cytokine-dependent gene expression and cellular development/survival is well established. Nevertheless, advances continue to be made in defining Jak-Stat pathway effects on different cellular processes and in different organisms. This review focuses on recent advances in the field and highlights some of the most active areas of Jak-Stat pathway research.
Medical subject headings
- Cytokines
- DNA-Binding Proteins
- Intracellular Signaling Peptides and Proteins
- Protein-Tyrosine Kinases
- Repressor Proteins
- Signal Transduction
- Trans-Activators