Ectopic D-type cyclin expression induces not only DNA replication but also cell division in Arabidopsis trichomes.
basic_science · Level V
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- Record sourced from PubMed, PMID 11983922.
- Also identified by PMC identifier 122962.
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Abstract
Although the mechanisms controlling the two cell-cycle checkpoints G(1)-S and G(2)-M are well studied, it remains elusive how they are linked in higher eukaryotes. In animals, D-type cyclins have been implicated in the control of cell-cycle progression in mitotic as well as in endoreduplicating cells. By contrast, we show that the expression of the D-type cyclin CYCD3;1 in endoreduplicating Arabidopsis trichome cells not only induced DNA replication but also cell divisions.
Medical subject headings
- Arabidopsis
- Cyclins
- DNA