Primary biliary cirrhosis: seeking the silent partner of autoimmunity.

Sutton, I; Neuberger, J · Gut · 2002

review · Level V

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Abstract

Primary biliary cirrhosis is a disorder characterised by an intense inflammatory response in the septal and interlobular bile ducts and is considered to be an autoimmune disease. Evidence to suggest that chronic viral infection could be a crucial element in the development of biliary epithelial cell damage and activation of the associated autoimmune response is reviewed

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