The association of pre-eclampsia with the Duffy negative phenotype in women of West African descent.
retrospective_cohort · Level III
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Abstract
To investigate whether pre-eclampsia in Curaçao is associated with the Duffy negative phenotype. Retrospective study. Women with a history of pre-eclampsia had a higher Duffy negative phenotype frequency compared with women with a history of uncomplicated pregnancies (52.8 vs 27.3%, respectively; odds ratio 2.98; 95% CI 1.40-6.32; P = 0.004). Pre-eclampsia is associated with the Duffy negative phenotype in women of West-African descent in the island of Curaçao.
Medical subject headings
- Duffy Blood-Group System
- Pre-Eclampsia