Propylene glycol toxicity associated with lorazepam infusion in a patient receiving continuous veno-venous hemofiltration with dialysis.
case_report · Level V
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- Record sourced from PubMed, PMID 12032031.
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Abstract
We report a case of toxicity from the drug solvent propylene glycol resulting from prolonged, large-dose lorazepam infusion. The case is unusual in that toxicity developed during continuous veno-venous hemofiltration with dialysis, a renal replacement therapy that should been have been effective at eliminating the chemical and its metabolites.
Medical subject headings
- GABA Modulators
- Hemofiltration
- Lorazepam
- Propylene Glycol
- Renal Dialysis