Treatment of Scedosporium apiospermum brain abscesses with posaconazole.

Mellinghoff, Ingo K; Winston, Drew J; Mukwaya, Geoffrey; Schiller, Gary J · Clin Infect Dis · 2002

case_report · Level V

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Abstract

A 41-year-old man with acute lymphoblastic leukemia developed multiple Scedosporium apiospermum brain abscesses. The infection progressed despite neurosurgical drainage and treatment with itraconazole, amphotericin B, and ketoconazole, but the brain abscesses completely resolved after treatment with posaconazole alone.

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