Generalized pustular and erythrodermic psoriasis associated with bupropion treatment.
case_report · Level V
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- Record sourced from PubMed, PMID 12072078.
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Abstract
Severe drug eruptions may cause diagnostic and therapeutic difficulty when they mimic or provoke endogenous patterns of dermatosis. We report three patients with known psoriasis in whom use of bupropion (Zyban), prescribed to assist with cessation of smoking, led to severe pustular or erythrodermic exacerbation of psoriasis within 3-5 weeks. All patients were systemically unwell and required hospitalization to control the disease flare.
Medical subject headings
- Bupropion
- Dermatitis, Exfoliative
- Dopamine Uptake Inhibitors
- Drug Eruptions
- Psoriasis
- Smoking Cessation