Destabilizing influences in apoptosis: sowing the seeds of IAP destruction.
basic_science · Level V
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Abstract
Inhibitor of apoptosis proteins (IAPs) can block apoptosis through interactions with members of the caspase family of cysteine proteases. Recent developments suggest that ubiquitin-proteasome mediated destruction of the Drosophila IAP, DIAP1, is a key event during the initiation of programmed cell death in the fly.
Medical subject headings
- Apoptosis
- Drosophila
- Drosophila Proteins