Multifocal motor neuropathy and Campylobacter jejuni reactivity.
cross_sectional · Level IV
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Abstract
In some patients, Campylobacter jejuni infection has been associated with the development of multifocal motor neuropathy (MMN) and high titers of antiganglioside antibodies. The authors measured anti-C. jejuni antibodies by ELISA and immunoblot in 20 patients with MMN, and correlated their presence with antiganglioside reactivity and a history of recent diarrhea. Only one patient had high titers of anti-C. jejuni antibodies, indicating that C. jejuni is unlikely to be involved in the pathogenesis of MMN in most patients.
Medical subject headings
- Antibodies, Bacterial
- Campylobacter Infections
- Campylobacter jejuni
- Gangliosides
- Polyneuropathies