Immunoglobulin levels in methotrexate treated paediatric rheumatology patients.

Rackham, O J; Sills, J A; Davidson, J E · Arch Dis Child · 2002

retrospective_cohort · Level III

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Abstract

Retrospective review of serum immunoglobulin levels in 78 methotrexate treated paediatric rheumatology patients showed that IgG, IgA, and IgM levels fell significantly by 26%, 21%, and 17% respectively while on methotrexate. Six patients with systemic disease showed a fall in IgG to below the normal range.

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