Chronic obstructive pulmonary disease. 1: Susceptibility factors for COPD the genotype-environment interaction.
review · Level V
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- Record sourced from PubMed, PMID 12149538.
- Also identified by PMC identifier 1746410.
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Abstract
Genetic factors including alpha(1)-antitrypsin deficiency are important in COPD. Candidate gene association studies in COPD are reviewed. Efforts to identify interactions between genetic factors and environmental determinants such as smoking may lead to improved understanding of the pathogenesis of the disease.
Medical subject headings
- Pulmonary Disease, Chronic Obstructive