Exploring the neighborhood: adhesion-coupled cell mechanosensors.
review · Level V
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- Record sourced from PubMed, PMID 12150922.
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Abstract
Here we discuss recent studies addressing adhesion-coupled mechanosensory processes and consider their molecular nature. Are cells using stretch-activated ion channels to explore the extracellular environment surrounding them, or do they use for that purpose the submembrane protein network that interconnects integrin receptors with the actin cytoskeleton?
Medical subject headings
- Focal Adhesions
- Mechanoreceptors