Intracranial perineural extension of invasive mycosis: a novel mechanism of disease propagation by Aspergillus fumigatus.

Safdar, Amar; Dommers, Martin P; Talwani, Rohit; Thompson, Charlotte R · Clin Infect Dis · 2002

case_report · Level V

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Abstract

We describe an immunocompetent woman who had refractory, invasive sphenoid sinus Aspergillus fumigatus infection for which there was radiologic evidence of intracranial perineural spread. The patient responded to a combination of antifungal and adjuvant recombinant cytokine therapy.

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