Extravascular necrotizing palisaded granulomas as the presenting skin sign of systemic lupus erythematosus.
case_report · Level V
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Abstract
We recently examined a patient who presented clinically with tender, erythematous papules associated with a febrile illness and polyarthralgias. Histopathological examination revealed extravascular palisaded neutrophilic granulomas, a skin reaction pattern originally described in Churg-Strauss disease but subsequently observed in a variety of other systemic disorders characterized by immune complex generation. A diagnosis of systemic lupus erythematosus (SLE) was established. To our knowledge, this is the first report of extravascular necrotizing palisaded granulomas as the presenting skin sign of SLE.
Medical subject headings
- Granuloma
- Lupus Erythematosus, Systemic