Neuropathologic findings in a Guillain-Barré patient with strokes after IVIg therapy.
case_report · Level V
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- Record sourced from PubMed, PMID 12177388.
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Abstract
Strokes have been rarely associated with immunoglobulin G (IVIg) therapy. A 70-year-old woman with stable polycythemia vera developed Guillain-Barré syndrome and received IVIg, 8 days following which she became comatose due to bilaterally symmetric cerebral infarcts. Autopsy showed intravascular aggregates of fibrin-IgG but also platelets and a necrotizing microangiopathy in the infarcts.
Medical subject headings
- Guillain-Barre Syndrome
- Immunoglobulins, Intravenous
- Stroke