Necrotizing granulomatous vasculitis associated with cocaine use.

Gertner, Elie; Hamlar, Dave · J Rheumatol · 2002

case_report · Level V

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Abstract

Cocaine abuse may be associated with a destructive nasal and pharyngeal process felt to be due to ischemia secondary to vasoconstriction. This report is the first to document a necrotizing granulomatous vasculitis associated with nasal destruction and an oronasal fistula in a chronic cocaine user. Cocaine is an environmental insult that may play a role in triggering cerebral and non-cerebral vasculitis including a necrotizing granulomatous vasculitis of the respiratory tract.

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