Primary meningeal osteosarcoma: case report and review of the literature.

Abstract

Primary meningeal osteosarcomas are extremely rare lesions; before this case report, only five cases had been reported in the literature. We encountered a patient with a meningeal osteosarcoma but no evidence of additional tumor at another remote site. A 56-year-old man presented with progressive weakness of the right leg and the right arm. Computed tomography and magnetic resonance imaging revealed an extracerebral frontoparietal tumor on the left side. The patient underwent complete resection of the tumor and subsequent radiotherapy of the tumor region. The histological examination showed evidence of the osteosarcoma, which was confined to the meninges. Postoperative adjuvant radiotherapy was administered. There was no tumor recurrence during 3 years of postoperative follow-up. Because the patient had no risk factors or further osteosarcomas, primary meningeal development was assumed. Despite their rarity, osteosarcomas must be considered in the differential diagnosis of meningeal tumors.