Temporal lobectomy for epilepsy: recovery of the contralateral hippocampus measured by (1)H MRS.
case_series · Level IV
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- Record sourced from PubMed, PMID 12196667.
- Also identified by PMC identifier 2753242.
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Abstract
(1)H MRS imaging was obtained from 10 patients with mesial temporal lobe epilepsy before and after surgery. After surgery, metabolic recovery in the contralateral hippocampus was detected. Preoperatively, reduced N-acetylaspartate (p < 0.04) increased after surgery nonsignificantly to equal control values. Cholines increased after surgery (p < 0.02) and creatine-phosphocreatine showed a trend to higher values. The results suggest that the contralateral hippocampus is affected by repeated seizure activity in the ipsilateral hippocampus, rather than presence of bilateral mesial temporal sclerosis.
Medical subject headings
- Aspartic Acid
- Epilepsy, Temporal Lobe
- Hippocampus
- Magnetic Resonance Spectroscopy
- Neurosurgical Procedures
- Recovery of Function