Issues in the design and interpretation of minimum alveolar anesthetic concentration (MAC) studies.

Sonner, James M · Anesth Analg · 2002

other · Level V

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Abstract

The two experimental designs (quantal and bracketing) used for population minimum alveolar anesthetic concentration studies give equivalent results. An expression relating variability in terms of Hill coefficients and SD is presented. Evolutionary implications of low population variability in anesthetic phenotypes is discussed.

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