Competition and compensation: coupled to death in development and cancer.
review · Level V
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Abstract
Developing systems exhibit robust and tolerant properties in the form of compensation and competition within cell groups. Fundamentally, these behaviors are governed by mechanisms that elicit proliferation and apoptosis. Recent insights from the Drosophila system implicate new determinants that specify "winners" and "losers" in this process.
Medical subject headings
- Apoptosis
- Cell Communication
- Cell Differentiation
- Cell Division
- Eukaryotic Cells
- Gene Expression Regulation, Developmental
- Neoplasms