UniBLAST: a system to filter, cluster, and display BLAST results and assign unique gene annotation.
basic_science · Level V
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- Record sourced from PubMed, PMID 12217921.
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Abstract
More and more often, a gene is epitomized by a large number of sequences in GenBank. This high redundancy makes it very difficult to identify a unique best match for a query sequence from its BLAST results. We developed a novel program UniBLAST that filters out uninformative hits, clusters the redundant hits, groups the hits by LocusLink, and graphically displays the results. We also implemented a scoring function in UniBLAST to assign a unique gene name to a query sequence. UniBLAST significantly increases the efficiency of gene annotation. The program is available at http://south.genomics.org.cn/software/uniblast/index.html uniblast@genomics.org.cn; wei@nexusgenomics.com
Medical subject headings
- Data Display
- Database Management Systems
- Databases, Nucleic Acid
- Genome
- Sequence Analysis, DNA
- User-Computer Interface