Acute infectious purpura fulminans associated with asplenism or hyposplenism.

Ward, Kimberley Morine; Celebi, Julide Tok; Gmyrek, Robyn; Grossman, Marc E · J Am Acad Dermatol · 2002

case_report · Level V

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Abstract

Acute infectious purpura fulminans is a rapidly progressive syndrome of hemorrhagic skin necrosis associated with acute infection and disseminated intravascular coagulation. We report 5 cases of purpura fulminans and briefly review the literature. All cases were associated with encapsulated organisms (Streptococcus pneumoniae or Group A streptococcus), and 4 of the 5 patients had asplenism or functional hyposplenism.

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