Assessment of the neurogenic flare reaction in small-fiber neuropathies.
cross_sectional · Level IV
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Abstract
To improve sensitivity of the analysis of axon reflex flare reaction, the authors used a laser Doppler scanner and analyzed flare intensity and size induced by histamine iontophoresis simultaneously at the foot and thigh in patients with small-fiber neuropathy (n = 10) and controls (n = 9). Flare size, but not laser Doppler flux, clearly distinguished patients from controls at both locations (p < 0.01) and may be useful for evaluation of small-fiber neuropathies.
Medical subject headings
- Axons
- Nerve Fibers
- Neurogenic Inflammation