A case-control study of HIV-1-related dementia and co-infection with HHV-8.

Polk, S; Muñoz, A; Sacktor, N C; Jenkins, F J; Cohen, B; Miller, E N; Jacobson, L P · Neurology · 2002

case_control · Level III

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Abstract

This nested case-control study assessed the putative protective effect of human herpesvirus-8 (HHV-8) against HIV-1-related dementia (dementia). The HHV-8 seropositivity of 210 male age- and HIV disease stage-matched cases and controls was compared. The overall HHV-8 seropositivity of 66% was similar among demented HIV-infected cases and nondemented HIV-infected controls.

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