Acute autoimmune hepatitis presenting with centrizonal liver disease: case report and review of the literature.

Singh, Ranvir; Nair, Satheesh; Farr, Gist; Mason, Andrew; Perrillo, Robert · Am J Gastroenterol · 2002

case_report · Level V

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Abstract

Relatively little is known about the histological appearance of autoimmune hepatitis during the early stage of disease. We describe a case of autoimmune hepatitis in a 20-yr-old woman in which the initial liver biopsy was characterized by a marked predominance of centrizonal injury. Over the course of several months, the histological appearance evolved to what is more commonly associated with chronic autoimmune hepatitis. A review of the literature on this interesting entity is presented.

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