Fat oxidation defect presenting with overwhelming ketonuria.

Wraige, E; Champion, M P; Turner, C; Dalton, R N · Arch Dis Child · 2002

case_report · Level V

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Abstract

Ketonuria accompanying hypoglycaemia is conventionally thought to exclude fat oxidation defects. We describe a 2 year old girl with hypoglycaemic encephalopathy in whom a diagnosis of very long chain acyl CoA dehydrogenase deficiency was suggested on the basis of acylcarnitine analysis despite massive ketonuria.

Medical subject headings