Endocytosis: driving membranes around the bend.
basic_science · Level V
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- Record sourced from PubMed, PMID 12408856.
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Abstract
When a nascent vesicle buds, the membrane must curve. Several mechanisms have been proposed for curvature creation or stabilization. Structural analysis of the ENTH domain of the endocytic protein epsin has suggested a new mechanism, in which the ENTH domain pushes its way into membranes, thus bending them into shape.
Medical subject headings
- Carrier Proteins
- Cell Membrane
- Endocytosis
- Neuropeptides
- Vesicular Transport Proteins