SNOMAD (Standardization and NOrmalization of MicroArray Data): web-accessible gene expression data analysis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 12424128.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
SNOMAD is a collection of algorithms for the normalization and standardization of gene expression datasets derived from diverse biological and technological sources. In addition to conventional transformations and visualization tools, SNOMAD includes two non-linear transformations which correct for bias and variance which are non-uniformly distributed across the range of microarray element signal intensities: (1). Local mean normalization; and (2). Local variance correction (Z-score generation using a locally calculated standard deviation).
Medical subject headings
- Database Management Systems
- Databases, Nucleic Acid
- Gene Expression Profiling
- Internet
- Oligonucleotide Array Sequence Analysis
- Sequence Analysis, DNA