GeneCards 2002: towards a complete, object-oriented, human gene compendium.

Safran, Marilyn; Solomon, Irina; Shmueli, Orit; Lapidot, Michal; Shen-Orr, Shai; Adato, Avital; Ben-Dor, Uri; Esterman, Nir et al. · Bioinformatics · 2002

other · Level V

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Abstract

In the post-genomic era, functional analysis of genes requires a sophisticated interdisciplinary arsenal. Comprehensive resources are challenged to provide consistently improving, state-of-the-art tools. GeneCards (Rebhan et al., 1998) has made innovative strides: (a). regular updates and enhancements incorporating new genes enriched with sequences, genomic locations, cDNA assemblies, orthologies, medical information, 3D protein structures, gene expression, and focused SNP summaries; (b). restructured software using object-oriented Perl, migration to schema-driven XML, and (c). pilot studies, introducing methods to produce cards for novel and predicted genes.

Medical subject headings