Poxvirus Orthologous Clusters (POCs).

Ehlers, Angelika; Osborne, John; Slack, Stephanie; Roper, Rachel L; Upton, Chris · Bioinformatics · 2002

basic_science · Level V

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Abstract

Poxvirus Orthologous Clusters (POCs) is a JAVA client-server application which accesses an updated database containing all complete poxvirus genomes; it automatically groups orthologous genes into families based on BLASTP scores for assessment by a human database curator. POCs has a user-friendly interface permitting complex SQL queries to retrieve interesting groups of DNA and protein sequences as well as gene families for subsequent interrogation by a variety of integrated tools: BLASTP, BLASTX, TBLASTN, Jalview (multiple alignment), Dotlet (Dotplot), Laj (local alignment), and NAP (nucleotide to amino acid alignment).

Medical subject headings