Effect on mood of subthalamic DBS for Parkinson's disease: a consecutive series of 24 patients.

Berney, A; Vingerhoets, F; Perrin, A; Guex, P; Villemure, J-G; Burkhard, P R; Benkelfat, C; Ghika, J · Neurology · 2002

case_series · Level IV

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Abstract

A series of 24 consecutive PD patients were prospectively studied prior to and within 6 months postoperatively for mood, motor, and cognitive status to investigate the effects on mood of subthalamic deep brain stimulation (DBS) in PD. In six patients (25%), mood state worsened significantly, and three were transiently suicidal despite clear motor improvement. Caregivers and patients should be educated about the potential impact of this neurosurgical procedure on mood.

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